874-54-4

Basic information

• Product Name: 1-Oxylato-3-carboxypyrazine-1-ium
• Synonyms: 1-Oxylato-3-carboxypyrazine-1-ium;2-Pyrazinecarboxylic acid 4-oxide;3-Carboxypyrazine 1-oxide;3-Pyrazinecarboxylic acid 1-oxide;Pyrazine-3-carboxylic acid 1-oxide
• CAS NO: 874-54-4
• Molecular Formula: C₅H₄N₂O₃
• Molecular Weight: 140.1
• Product Categories: Aromatics;Heterocycles;Miscellaneous Reagents
• Mol File: 874-54-4.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Storage Temp.: Amber Vial, Refrigerator
• Solubility: DMSO, Water
• CAS DataBase Reference: 1-Oxylato-3-carboxypyrazine-1-ium(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Oxylato-3-carboxypyrazine-1-ium(874-54-4)
• EPA Substance Registry System: 1-Oxylato-3-carboxypyrazine-1-ium(874-54-4)

Safety Data

• Hazardous Substances Data: 874-54-4(Hazardous Substances Data)

Usage

Chemical Properties

White Solid

Uses

2-Pyrazinecarboxylic Acid 4-Oxide (cas# 874-54-4) is a compound useful in organic synthesis.

Upstream product

• 109-08-0 2-Methylpyrazine 

Downstream Products

• 148673-71-6 6-chloropyrazine-2-carboxylic acid chloride 
• 23688-89-3 6-chloropyrazine-2-carboxylic acid 
• 770-00-3 methylester of pyrazinecarboxylic acid 4-oxide 

Relevant articles and documents

Facile, one-step production of niacin (vitamin B3) and other nitrogen-containing pharmaceutical chemicals with a single-site heterogeneous catalyst

Niacin (3-picolinic acid), which is extensively used as vitamin B 3 in foodstuffs and as a cholesterol-lowering agent, along with other oxygenated products of the picolines, 4-methylquinoline, and a variety of pyrimidines and pyridazines, may be produced in a single-step, environmentally benign fashion by combining single-site, open-structure, heterogeneous catalysts witha solid source of active oxygen, namely acetyl peroxyborate (APB), in the absence of an organic solvent. The high activities, selectivities, and the relatively mild conditions employed with this single-site heterogeneous catalyst, coupled with ease of transport, storage, and stability of the solid oxidant, augurs well for the future use of APB in conjunction with other open-structure, single-site catalysts for fine-chemical, pharmaceutical, and agrochemical applications.