87407-53-2Relevant academic research and scientific papers
22-HALOACETOXY-HOMOPREGNACALCIFEROL ANALOGS AND THEIR USES
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Page/Page column 9-10, (2012/05/31)
This invention discloses 22-haloacetoxy-homopregnacalciferol analogs and specifically 22-bromoacetoxy-homopregnacalciferol and pharmaceutical uses therefor. This compound exhibits relatively little calcemic activity and does not promote cellular different
Probing the structural requirements for vitamin D3 inhibition of the hedgehog signaling pathway
Deberardinis, Albert M.,Banerjee, Upasana,Miller, Michele,Lemieux, Steven,Hadden
, p. 4859 - 4863 (2012/08/13)
A structure-activity relationship study to elucidate the structural basis for hedgehog (Hh) signaling inhibition by vitamin D3 (VD3) was performed. Functional and non-functional regions of VD3 and VD2 were obtained through straightforward synthetic means
