874117-65-4Relevant academic research and scientific papers
A mild and metal-free synthesis of chiral 2,3-dihydro-3-hydroxymethyl-1,4-benzoxazines
Zhao, Hongyi,Li, Shengnan,Cheng, Shihao,Lin, Ziyun,Zhang, Dongfeng,Huang, Haihong
, (2021/07/06)
Various functionalized enantiomerically pure 3-hydroxymethyl-1,4-benzoxazine derivatives, including four stereoisomers, were synthesized from chiral 2,3-epoxy-4-trityloxybutanol. The synthesis was mild and metal-free. Yields of 52%–94%, and stereoselectiv
Synthesis of a versatile (S)-3-(hydroxymethyl)butane-1,2,4-triol building block and its application for the stereoselective synthesis of N-homoceramides
Hillaert, Ulrik,Van Calenbergh, Serge
, p. 5769 - 5772 (2007/10/03)
(Chemical Equation Presented) A versatile (S)-3-(hydroxymethyl)butane-1,2, 4-triol building block has been synthesized starting from D-isoascorbic acid, a common food preservative. The key transformation in this approach was the introduction of branching
