874125-06-1

Basic information

• Product Name: C₂₀H₂₄BrN₃O₇S₂*ClH
• Synonyms: C₂₀H₂₄BrN₃O₇S₂*ClH
• CAS NO: 874125-06-1
• Molecular Weight: 598.923
• Mol File: 874125-06-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₀H₂₄BrN₃O₇S₂*ClH(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₀H₂₄BrN₃O₇S₂*ClH(874125-06-1)
• EPA Substance Registry System: C₂₀H₂₄BrN₃O₇S₂*ClH(874125-06-1)

Safety Data

• Hazardous Substances Data: 874125-06-1(Hazardous Substances Data)

Upstream product

• 874124-85-3 C₂₅H₃₂BrN₃O₉S₂ 

Downstream Products

• 874125-07-2 C₂₆H₃₄BrN₃O₈S₂ 

Relevant articles and documents

HEPATITIS C INHIBITOR DIPEPTIDE ANALOGS

The present invention relates to compounds of formula (I): wherein R1, R2, R4, n and m are as defined herein and R3 is selected from: (i) -C(O)OR31 wherein R31 is (C1-6)alkyl or aryl, wherein the (C1-6)alkyl is optionally substituted with one to three halogen substituents; (ii) -C(O)NR32R33, wherein R32 and R33 are each independently selected form H, (C1-6)alkyl, and Het; (iii) -SOvR34, wherein v is 1 or 2 and R34 is selected from: (C1-6)alkyl, aryl, Het, and NR32R33 wherein R32 and R33 are as defined above; and (iv) -CO(O)-R35, wherein R35 is selected from (C1-8)alkyl, (C3-7)cycloalkyl-(C1-4)alkyl, aryl, aryl-(C1-6)alkyl, Het and Het-(C1-6)alkyl, each of which are optionally substituted with one or more substituents each independently selected from halo, (C1-6)alkyl, (C3-7)cycloalkyl, aryl, Het, hydroxyl, -O-(C1-6)alkyl, -S-(C1-6)alkyl, -SO-(C1-6)alkyl, -SO2-(C1-6)alkyl, -O-aryl, -S-aryl, -SO-aryl and -SO2-aryl, wherein the aryl portion of the -O-aryl, -S-aryl, -SO-aryl and -SO2-aryl are each optionally substituted with one to five halo substituents. The present invention further relates to pharmaceutical compositions containing the compounds of formula (I) and methods for using these analogs in the treatment of HCV infection.