874152-82-6Relevant academic research and scientific papers
Synthetic approaches to 5,7-disubstituted imidazo[5,1-f][1,2,4]triazin-4-amines
Werner, Douglas S.,Dong, Hanqing,Kadalbajoo, Mridula,Laufer, Radoslaw S.,Tavares-Greco, Paula A.,Volk, Brian R.,Mulvihill, Mark J.,Crew, Andrew P.
scheme or table, p. 3899 - 3901 (2010/08/20)
The preparation of 5,7-disubstituted imidazo[5,1-f][1,2,4]triazin-4-amines, exemplified by 5-[3-(benzyloxy)phenyl]-7-cyclobutylimidazo[5,1-f][1,2,4]triazin-4-amine, was developed through a linear and three convergent synthetic strategies, with the latter providing the greatest flexibility for diversification at the 5-position at the last step of the synthesis.
