874213-29-3Relevant academic research and scientific papers
Synthesis and preliminary in vitro investigation of bivalent ligands containing homo- and heterodimeric pharmacophores at μ, δ, and κ opioid receptors
Peng, Xuemei,Knapp, Brian I.,Bidlack, Jean M.,Neumeyer, John L.
, p. 256 - 262 (2007/10/03)
A series of homo- and heterodimeric ligands containing κ agonist and μ agonist/antagonist pharmacophores joined by a linker chain of varying lengths was synthesized and evaluated in vitro by their binding affinity at μ, δ, and κ opioid receptors. The func
