874216-24-7Relevant articles and documents
Synthesis and activity of a new class of pathway-selective estrogen receptor ligands: Hydroxybenzoyl-3,4-dihydroquinoxalin-2(1H)-ones
Mahaney, Paige E.,Webb, Michael B.,Ye, Fei,Sabatucci, Joseph P.,Steffan, Robert J.,Chadwick, Christopher C.,Harnish, Douglas C.,Trybulski, Eugene J.
, p. 3455 - 3466 (2006)
The anti-inflammatory activity of non-selective estrogens has been attributed to their ability to antagonize the activity of nuclear factor κB (NF-κB), a known mediator of inflammatory responses. Here we report the identification of a potent new class of