874289-42-6 Usage
Description
2-Fluoro-5-(pyrrolidine-1-carbonyl)phenylboronic acid is an organic boronic acid compound characterized by the presence of a fluorine atom at the 2nd position and a pyrrolidine-1-carbonyl group at the 5th position on a phenyl ring. This unique structure endows it with specific chemical properties and potential applications in various fields.
Uses
Used in Pharmaceutical Industry:
2-Fluoro-5-(pyrrolidine-1-carbonyl)phenylboronic acid is used as a key intermediate in the synthesis of heteroaryl compounds, which serve as inhibitors of PI3K (phosphoinositide 3-kinase) and/or mTOR (mechanistic target of rapamycin) pathways. These pathways play crucial roles in cell growth, proliferation, and survival, and their dysregulation is often associated with various diseases, including cancer, inflammatory conditions, and cardiovascular disorders.
By targeting these pathways, the resulting heteroaryl inhibitors can potentially be developed into therapeutic agents for the treatment of proliferative, inflammatory, or cardiovascular disorders, offering new treatment options and improving patient outcomes in these areas.
Check Digit Verification of cas no
The CAS Registry Mumber 874289-42-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,7,4,2,8 and 9 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 874289-42:
(8*8)+(7*7)+(6*4)+(5*2)+(4*8)+(3*9)+(2*4)+(1*2)=216
216 % 10 = 6
So 874289-42-6 is a valid CAS Registry Number.
InChI:InChI=1/C11H13BFNO3/c13-10-4-3-8(7-9(10)12(16)17)11(15)14-5-1-2-6-14/h3-4,7,16-17H,1-2,5-6H2