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CAS

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87429-26-3

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87429-26-3 Usage

Physical state

White solid

Molecular weight

176.21 g/mol

Potential pharmaceutical applications

Studied for potential use in treating epilepsy and neurodegenerative diseases

Properties

Demonstrated anti-inflammatory and anticonvulsant properties in preclinical studies

Development potential

Promising candidate for the development of new drugs

Research status

Further research needed to fully understand therapeutic effects and safety profile

Check Digit Verification of cas no

The CAS Registry Mumber 87429-26-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,7,4,2 and 9 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 87429-26:
(7*8)+(6*7)+(5*4)+(4*2)+(3*9)+(2*2)+(1*6)=163
163 % 10 = 3
So 87429-26-3 is a valid CAS Registry Number.

87429-26-3Relevant articles and documents

Synthesis and antitumor activities of chiral dipeptide thioureas containing an alpha-aminophosphonate moiety

Liu, Jingzi,Liao, Peng,Hu, Junfeng,Zhu, Hong,Wang, Yonglin,Li, Yongjun,Li, Yan,He, Bin

, (2017/02/26)

Thiourea derivatives demonstrate potent cytotoxic activity against various leukemias and many tumor cell lines. In our previous study, the combination of thiourea and phosphonate has been proven as an effective strategy for developing antitumor agents. Herein, we synthesized and evaluated a series of novel chiral dipeptide thioureas containing an α-aminophosphonate moiety as antitumor agents. Finally, we developed novel dipeptide thioureas 11d and 11f that showed comparable inhibition with that of Cisplatin against BGC-823 and A-549 cells, respectively.

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