874350-10-4

Upstream product

• 633294-28-7 (1R,3R,5R)-3-(tert-butyldimethylsilyloxy)-5-(tert-butyldiphenylsilyloxy)-2-methylenecyclohexanol 
• 874350-08-0 (3R,4R,6R,8R)-8-(tert-butyldimethylsilyloxy)-6-(tert-butyldiphenylsilyloxy)-4-(trimethylsilyloxy)-1-oxaspiro[2.5]octane 
• 874350-09-1 (1R,2R,4R,6R)-2-(tert-butyldimethylsilyloxy)-4-(tert-butyldiphenylsilyloxy)-1-[(2-phenyl-1,3-dithian-2-yl)methyl]-6-(trimethylsilyloxy)-cyclohexan-1-ol 

Downstream Products

• 874350-13-7 (2S,3R,5S)-2,3,5-Trihydroxy-2-(2-phenyl-[1,3]dithian-2-ylmethyl)-cyclohexanone 
• 874350-06-8 (2S,3R,5S)-3-(tert-butyldimethylsilyloxy)-5-(tert-butyldiphenylsilyloxy)-2-[(2-phenyl-1,3-dithian-2-yl)methyl]-2-hydroxycyclohexan-1-one 

Relevant academic research and scientific papers

Diastereoselective reactions at enantiomerically pure, sterically congested cyclohexanes as an entry to wailupemycins A and B: Total synthesis of (+)-wailupemycin B

Wailupemycin A (1) and B (2) are polyketide natural products with a highly substituted cyclohexanone core. Three different routes for the syntheses of these compounds were pursued, which commenced from either (R)-(-)-carvone (ent-5) or (S)-(+)-carvone (5)