874362-76-2Relevant academic research and scientific papers
Selective Hydrogenation by Carbocatalyst: The Role of Radicals
Ahmad, Muhammad Sohail,He, Huixin,Nishina, Yuta
supporting information, p. 8164 - 8168 (2019/10/16)
The selective hydrogenation of the nitro moiety is a difficult task in the presence of other reducible functional groups such as alkenes or alkynes. We show that the carbon-based (metal-free) catalyst can be used to selectively reduce substituted nitro groups using H2 as a reducing agent, providing a great potential to replace noble-metal catalysts and contributing to simple and greener strategies for organic synthesis.
A two stage click-based library of protein tyrosine phosphatase inhibitors
Xie, Jian,Seto, Christopher T.
, p. 458 - 473 (2008/02/10)
Protein tyrosine phosphatases (PTPs) are important regulators of signal transduction pathways. Potent and selective PTP inhibitors are useful for probing these pathways and also may serve as drugs for the treatment of a variety of diseases including type
