87439-73-4Relevant academic research and scientific papers
Design, synthesis, and pharmacological characterization of some 2-substituted-3-phenyl-quinazolin-4(3H)-one derivatives as phosphodiesterase inhibitors
Amin, Kamilia M.,Hegazy, Gehan H.,George, Riham F.,Ibrahim, Nahla R.,Mohamed, Nada M.
, (2021/05/13)
Some 3-phenyl-quinazolin-4(3H)-one-2-thioethers (3a–e, 5a,b, 7a–e, 9a–d, 10a–d, and 12) along with 2-aminoquinazoline derivatives 13a–c were prepared and screened for their in vitro phosphodiesterase (PDE) inhibitory activity. Some compounds such as 7d,e,
Synthesis of 5-Mercapto-1,2,4-triazole Derivatives Containing 4(3H)-Quinazolone Nucleus
Mahmoud, A. M.,El-Sherief, H. A. H.,El-Naggar, G. M.,Abdel-Rahman, A. E.
, p. 491 - 493 (2007/10/02)
3-(3,4-Dihydro-4-oxo-3-phenylquinazolin-2-ylmercaptomethyl)-5-mercapto-4-phenyl-1,2,4-triazole (VII) and 3-(3,4-dihydro-4-oxo-3-phenylquinazolin-2-ylmercaptopropyl)-5-mercapto-4-phenyl-1,2,4-triazole (VIII) have been synthesized.S-Alkylation of VII and VIII and the reaction of VIII with N-arylchloroacetamides and N1-chloroacetyl-N2-arylureas have been carried out.
