874444-13-0Relevant academic research and scientific papers
Syntheses of some novel imidazolidinethiones and condensed imidazoles containing arylazo moieties starting from cyanothioformamides
El-Sharief, Ahmed M.Sh.,El-Gaby, Mohamed S.A.,Atalla, Ahmed A.,El-Adasy, Abu-Bakr A.A.M.
, p. 218 - 225 (2005)
Cyclocondensation of cyanothioformamides (1) with arylhydrazonomalononitriles (2) afforded the novel imidazole derivatives (4a-e) in good yields. Isothiocyanatoazobenzene (6) was allowed to react with potassium cyanide and gave the new cyanothioformamide (7) which was reacted with 4-chlorophenyl isocyanate to yield imidazolidinethione (8). Compound (8) was subjected to react with hydrochloric acid, o-phenylenediamine, 4-methylaniline, and hydrogen sulfide and furnished compounds (10), (11), (12), and (15), respectively. Also, the reactivity of thiohydantoin (15) toward some electrophilic reagents such as N,N-dimethylformamide-dimethyl-acetal and arylidene-malononitriles was investigated. The structure of the synthesized compounds was established by analytical and spectral data.
