874459-33-3Relevant academic research and scientific papers
Bioisosteric heterocyclic versions of 7-{[2-(4-phenyl-piperazin-1-yl)ethyl] propylamino}-5,6,7,8-tetrahydronaphthalen-2-ol: Identification of highly potent and selective agonists for dopamine D3 receptor with potent in vivo activity
Biswas, Swati,Hazeldine, Stuart,Ghosh, Balaram,Parrington, Ingrid,Kuzhikandathil, Eldo,Reith, Maarten E. A.,Dutta, Aloke K.
experimental part, p. 3005 - 3019 (2009/04/06)
In the current report, we extend the SAR study on our hybrid structure 7-{[2-(4-phenyl-piperazin-1-yl)ethyl]propylamino}-5,6,7,8-tetrahydronaphthalen- 2-ol further to include heterocyclic bioisosteric analogues. Binding assays were carried out with HEK-29
