874491-64-2Relevant academic research and scientific papers
PYRIDINYL SULFONAMIDE MODULATORS OF CHEMOKINE RECEPTORS
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Page/Page column 21-22, (2010/11/27)
The present invention relates to compounds of following formula (I) or pharmaceutically acceptable salts thereof; pharmaceutical compositions containing them, and their use in the treatment of disorders mediated by the CCR-2 receptor.
HETEROARYL SULFONAMIDES AND CCR2
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Page/Page column 96-97, (2008/06/13)
Compounds are provided that act as potent antagonists of the CCR2 receptor. Animal testing demonstrates that these compounds are useful for treating inflammation, a hallmark disease for CCR2. The compounds are generally aryl sulfonamide derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR2-mediated diseases, and as controls in assays for the identification of CCR2 antagonists.
