87451-14-7Relevant academic research and scientific papers
Carbonylative Ring Expansion of Aziridines to β-Lactams with Rhodium-Complexed Dendrimers on a Resin
Lu, Shui-Ming,Alper, Howard
, p. 3558 - 3561 (2007/10/03)
Rhodium-complexed dendrimers, supported on a resin, were evaluated as catalysts for the carbonylative ring expansion reactions of a variety of aziridines with carbon monoxide to give β-lactams. The effects of reaction temperature, solvent, time, and press
Enantiospecific and Stereospecific Rhodium(I)-Catalyzed Carbonylation and Ring Expansion of Aziridines. Asymmetric Synthesis of β-Lactams and the Kinetic Resolution of Aziridines
Calet, Serge,Urso, Fabio,Alper, Howard
, p. 931 - 934 (2007/10/02)
Rhodium(I) complexes catalyze the regiospecific ring expansion-carbonylation reaction of aziridines to β-lactams.This process is both stereospecific and enantiospecific, occuring with retention of configuration e.g., (S)-1-tert-butyl-2-phenylaziridine is
