874525-74-3

Upstream product

• 4294-57-9 para-methylphenylmagnesium bromide 
• 123-73-9 crotonaldehyde 

Downstream Products

• 4160-52-5 1-(4-methylphenyl)butan-1-one 
• 3837-95-4 (E)-1-(4-methylphenyl)-2-buten-1-one 
• 1360472-55-4 (R)-2-methyl-4-oxo-4-(p-tolyl)butanenitrile 
• 1331781-29-3 (S)-2-methyl-4-oxo-4-(p-tolyl)butanenitrile 
• 1181267-64-0 2-methyl-4-oxo-4-(p-tolyl)butanenitrile 
• 131029-21-5 (Z)-1-methoxy-1-tolylbut-2-ene 
• 131029-22-6 (E)-1-methoxy-1-tolylbut-2-ene 

Relevant academic research and scientific papers

Structural study-guided development of versatile phase-transfer catalysts for asymmetric conjugate additions of cyanide

Unprecedented phase-transfer catalysts for the first example of an organocatalytic asymmetric conjugate addition of cyanide with acetone cyanohydrin are reported (see scheme). Utilizing an accessible cupreidinium salt and a cyanation reagent suitable for industrial scale, this reaction holds significant promise for practical asymmetric synthesis. The catalysts were developed as a result of key structural insights gained by X-ray analysis. Copyright

Photolysis of 1,1,1-Triarylalk-2-enes and 1,1,1-Triarylhept-2-ynes. A Novel Generation of Aryl(alk-1-enyl)carbenes ans Aryl(alk-1-ynyl)carbenes

Upon UV irradiation in methanol, 1,1,1-triarylhept-2-ynes underwent an α,α-elimination of two aryl groups to give a biaryl and the corresponding carbene which reacted with methanol to give a 1-aryl-1-methoxyhept-2-yne. 1,1,1-Triphenylalk-2-enes underwent α,α-elimination of two phenyl groups and also elimination of an alkene and a phenyl group to give biphenyl and a 1-phenylalkene respectively.In both cases, the corresponding carbenes were formed and were isolated as methanol insertion products (a 1-methoxy-1-phenylalk-2-ene and diphenylmethyl methyl ether, respectively).A rearrangement product, a 1,1,2-triphenylcyclopropane, was also formed.