874632-39-0Relevant academic research and scientific papers
Enantioselective total synthesis of macrolide antitumor agent (-)-lasonolide A
Ghosh, Arun K.,Gong, Gangli
, p. 1437 - 1440 (2008/02/03)
Equation presented An enantioselective total synthesis of (-)-lasonolide A is described. The upper tetrahydropyran ring was constructed stereoselectively by an intramolecular 1,3-dipolar cycloaddition reaction. The bicyclic isooxazoline led to the tetrahy
Efficient, scalable kinetic resolution of cis-4-benzyloxy-2,3-epoxybutanol
Faigl, Ferenc,Thurner, Angelika,Battancs, Melinda,Farkas, Ferenc,Poppe, Laszlo,Bodai, Viktoria,Kmecz, Ildiko,Simandi, Bela
, p. 3841 - 3847 (2007/10/03)
A new enzyme catalysed kinetic resolution of cis-4-benzyloxy-2,3- epoxybutanol has been reported. Efficient, scalable separation of the optically active alcohol from its ester derivative has been solved with liquid-liquid and solid-liquid extraction metho
Larger Scale Preparation of Optically-active Allylic Alcohols
Balmer, Ethnie,Germain, Andrew,Jackson, William P.,Lygo, Barry
, p. 399 - 400 (2007/10/02)
An efficient and practical synthesis of optically-active allylic alcohols from 2,3-epoxytoluene-p-sulfonates by the in situ formation of the epoxy iodides and their subsequent reduction with zinc-copper couple has been established.Application of this procedure to the larger-scale synthesis of (S)-(+)-but-3-en-2-ol from (2S,3S)-3-methylglycidyl toluene-p-sulfonate has also been investigated.
