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Usage

Uses

Used in Pharmaceutical Development:
4-Pyridin-4-ylpyrimidine-2(1H)-thione is utilized as a key component in drug discovery for its potential to exhibit significant biological activities. Its unique structure allows it to interact with various biological targets, making it a valuable candidate for the creation of new medications.
Used in Agricultural Chemicals:
In the agricultural sector, 4-Pyridin-4-ylpyrimidine-2(1H)-thione may serve as a building block for the development of novel agrochemicals. Its properties could be harnessed to create compounds that address specific needs in crop protection and enhancement.
Used in Materials Science:
4-Pyridin-4-ylpyrimidine-2(1H)-thione also has potential applications in materials science. It can be employed in the synthesis of innovative polymers and other materials, contributing to the advancement of material technologies and potentially leading to new products with improved properties.

Upstream product

• 1122-54-9 methyl (4-pyridyl) ketone 
• 123367-27-1 3-(dimethylamino)-1-(pyridin-4-yl)prop-2-en-1-one 
• 17356-08-0 thiourea 
• 4637-24-5 N,N-dimethyl-formamide dimethyl acetal 

Relevant academic research and scientific papers

A highly selective fluorescent probe based on coumarin and pyrimidine hydrazide for Cu2+ ion detection

A novel diethylamino coumarin Schiff base modified with a pyrimidine-hydrazide (EDMP) was synthesized as Cu2+ fluorescent probe. Its photophysical properties and recognition ability to Cu2+ were studied by UV–Vis, fluorescence, IR and mass spectrum. Under UV light, EDMP probe showed a strong bright green fluorescence. After introducing Cu2+, the probe solution was changed from light green to orange and the maximum absorption wavelength bathochromically shifted from 445 nm to 475 nm. Meanwhile, fluorescence quenching phenomenon was observed. Fluorescence titration experiment showed that EDMP exclusively reacted with Cu2+ and the stoichiometric ratio was 1:1. The lowest detection limit was calculated to be 1.153 μM by fitting the titration curve. Additionally, DFT calculation method was utilized to analyze the action mechanism of EDMP toward Cu2+.

Synthesis and antibacterial activity of a series of heterocyclic sulfonate ligands and their metal complexes

A series of heterocyclic sulfonate ligands and their barium(II), silver(I), manganese(II), zinc(II) and cobalt(II) coordination compounds have been synthesized. Through antibacterial activities experiments of these complex compounds, metal salts as well as ligands, the rational conclusion is arrived that antibacterial activities of these compounds come from metal ions.