87480-71-5Relevant academic research and scientific papers
Sila-Pharmaca, 37. - Preparation and Properties of the Enantiomers of the Antimuscarinic Agents Sila-Procyclidine and Sila-Tricyclamol Iodide: Optically Active Silanols with Silicon as the Centre of Chirality
Tacke, Reinhold,Linoh, Haryanto,Ernst, Ludger,Moser, Ulrich,Mutschler, Ernst,et al.
, p. 1229 - 1238 (2007/10/02)
The enantiomers of sila-procyclidine (R)-1b and (S)-1b 97percent ee (NMR), 99.7percent ee (DSC)> were obtained by resolution with L-(+)- and D-(-)-tartaric acid, respectively.Starting from (R)-1b and (S)-1b, the hydrochlorides (R)-2b and (S)-2b were pre
