874814-72-9Relevant articles and documents
LIGAND-ENABLED META-C-H ACTIVATION USING A TRANSIENT MEDIATOR
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Page/Page column 49; 50, (2016/08/23)
An alternative approach to formation of a C-C bond at a meta-position of an aromatic compound is disclosed that employs an ethylenically unsaturated bicyclic compound as a transient mediator to achieve meta-selective C-H activation with a simple and common ortho-directing group. The use of a pyridine-based ligand assists in relaying the palladium catalyst to the meta-position by the unsaturated bicyclic compound following initial ortho-C-H activation.