874905-04-1

Basic information

• Product Name: C₄₃H₅₃NO₁₉
• Synonyms: C₄₃H₅₃NO₁₉
• CAS NO: 874905-04-1
• Molecular Weight: 887.889
• Mol File: 874905-04-1.mol

Chemical Properties

• CAS DataBase Reference: C₄₃H₅₃NO₁₉(CAS DataBase Reference)
• NIST Chemistry Reference: C₄₃H₅₃NO₁₉(874905-04-1)
• EPA Substance Registry System: C₄₃H₅₃NO₁₉(874905-04-1)

Safety Data

• Hazardous Substances Data: 874905-04-1(Hazardous Substances Data)

Upstream product

• 78878-42-9 allyl 2-O-benzoyl-6-O-benzyl-α-D-galactopyranoside 
• 874904-90-2 methyl 5-acetamido-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-D-glycero-D-galacto-2-nonulopyranosonate 2-(N-phenyl)trifluoroacetimidate 

Relevant articles and documents

Reinvestigation of the C5-acetamide sialic acid donor for α-selective sialylation: Practical procedure under microfluidic conditions

Despite the previous literature describing the "low-to-modest" efficiency, the readily available C5-acetamide donor was reinvestigated for its use in α-sialylation under microfluidic conditions. The N-phenyltrifluoroacetimidate donor was efficiently mixed with an appropriate amount of TMSOTf to produce the α(2-6) and α(2-3)-sialylation products of galactose and glucosamine acceptors in excellent yields and with nearly perfect α-selectivity.

Efficient synthesis of the disialylated tetrasaccharide motif in N-glycans through an amide-protection strategy

A disialylated tetrasaccharide, Neu5Ac(α2,3)Gal(β1,3)[Neu5Ac(α2,6)]GlcNAc (1), which is found at the termini of some N-glycans, has been synthesized. Compound 1 was obtained through an α-sialylation reaction between a sialic acid donor and a trisaccharide