874961-90-7 Usage
Uses
Used in Pharmaceutical Industry:
2,4(1H,3H)-Pyrimidinedione, 6-chloro-5-[(3-chlorophenyl)methyl]is used as a building block for the synthesis of various drugs and biologically active molecules. Its unique chemical structure and properties make it a promising candidate for the development of new therapeutic agents and research in medicinal chemistry.
Used in Drug Discovery and Development:
The chemical properties and biological activities of 2,4(1H,3H)-Pyrimidinedione, 6-chloro-5-[(3-chlorophenyl)methyl]make it a valuable target for further study in drug discovery and development. Its potential applications in the development of new therapeutic agents highlight its importance in advancing the field of medicinal chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 874961-90-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,7,4,9,6 and 1 respectively; the second part has 2 digits, 9 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 874961-90:
(8*8)+(7*7)+(6*4)+(5*9)+(4*6)+(3*1)+(2*9)+(1*0)=227
227 % 10 = 7
So 874961-90-7 is a valid CAS Registry Number.
874961-90-7Relevant academic research and scientific papers
Discovery and optimization of novel, non-steroidal glucocorticoid receptor modulators
Ray, Nicholas C.,Clark, Robin D.,Clark, David E.,Williams, Karen,Hickin,Crackett, Peter H.,Dyke, Hazel J.,Lockey, Peter M.,Wong, Melanie,Devos, Rene,White, Anne,Belanoff, Joseph K.
, p. 4901 - 4905 (2008/12/22)
A virtual screening approach comprising a 3-D similarity search based on known GR modulators was used to identify a novel series of non-steroidal glucocorticoid receptor (GR) antagonists. Optimization of the initial hit to provide potent compounds which e
Modified pyrimidine glucocorticoid receptor modulators
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Page/Page column 18, (2008/06/13)
The present invention provides a novel class of modified pyrimidine compounds and compositions and methods of using the compounds as glucocorticoid receptor modulators.
