875110-87-5

Usage

Structure

A derivative of indole, containing a benzene ring fused to a pyrrole ring, with a methyl group attached to the 4-position of the benzene ring and an ethyl group attached to the 1-position of the benzene ring.

Usage

Used in the synthesis of pharmaceuticals and organic compounds, and in the production of perfumes and fragrances.

Biological activities

Antitumor, anti-inflammatory, and antimicrobial properties, and has been studied for its potential use in the treatment of cancer and other diseases.

Upstream product

• 496-15-1 1-indoline 
• 4748-78-1 4-ethylbenzylaldehyde 
• 1467-05-6 4-ethylbenzylchloride 

Downstream Products

• 875110-88-6 3-bromo-1-(4-ethylbenzyl)-1H-indole 

Relevant academic research and scientific papers

Redox isomerization via azomethine ylide intermediates: N-alkyl indoles from indolines and aldehydes

Indolines react with aromatic and heteroaromatic aldehydes to yield N-alkyl indoles in a benzoic acid catalyzed redox isomerization reaction. Azomethine ylides are intermediates in this process which was established by intramolecular [3 + 2] trapping expe

NOVEL CYCLOHEXANE DERIVATIVE, PRODRUG THEREOF AND SALT THEREOF, AND THERAPEUTIC AGENT CONTAINING THE SAME FOR DIABETES

A cyclohexane derivative having the function of reducing a blood sugar level and having preferable properties required of medicines, such as long-lasting drug activity, metabolic stability, and safety; and a medicinal composition for use in the prevention or treatment of diseases attributable to hyperglycemia, such as diabetes, e.g., insulin dependent diabetes mellitus (type 1 diabetes) or noninsulin-dependent diabetes mellitus (type 2 diabetes), complications of diabetes, and obesity. The derivative is a compound represented by the formula (I): (wherein A is -O-, -CH2-, or -NH-; n is an integer selected between 0 and 1; R6 and R7 each independently is hydrogen or C1-6 alkyl; m is an integer selected among 1-3; Q is selected among the following formulae Q1 to Q5; Ar1 is optionally substituted arylene or optionally substituted heteroarylene, provided that the heteroarylene may be bonded to an aromatic carbocycle or aromatic heterocycle to form a fused ring; and Ar2 is optionally substituted aryl or optionally substituted heteroaryl), a prodrug of the compound, or a pharmaceutically acceptable salt of either. Also provided are a medicine, a medicinal composition, or the like each containing the compound.