87520-00-1Relevant academic research and scientific papers
Stereochemistry of Intramolecular Amidoalkylation Reactions in the Synthesis of Polycyclic Isoquinoline Derivatives
Maryanoff, Bruce E.,McComsey, David F.,Duhl-Emswiler, Barbara A.
, p. 5062 - 5074 (1983)
N-Acyliminium cyclizations onto benzenoid rings to give tetrahydroisoquinoline ring systems were studied.Particular attention was paid to the stereochemical effect of substituents present on the isoquinoline ring.High stereoselectivity (> 90 percent) was
