875283-33-3Relevant academic research and scientific papers
A series of penicillin derived C2-symmetric inhibitors of HIV-1 proteinase: synthesis, mode of interaction, and structure-activity relationships.
Humber,Bamford,Bethell,Cammack,Cobley,Evans,Gray,Hann,Orr,Saunders,et al.
, p. 3120 - 3128 (2007/10/02)
The C2-symmetric diester 1 was identified by random screening as a novel inhibitor of HIV-1 proteinase. This led to the preparation of a series of related more potent amides from readily accessible penicillins. Many of the compounds showed potent antivira
