875305-86-5 Usage
Uses
Used in Pharmaceutical Research and Development:
7-Bromo-5-chloro-1H-indazole is used as a key intermediate in the synthesis of pharmaceutical drugs for various therapeutic applications. Its unique structure and biological activities make it a promising candidate for the development of new drugs with improved efficacy and safety profiles.
Used in Agrochemical Development:
In the agrochemical industry, 7-Bromo-5-chloro-1H-indazole is utilized as a starting material for the synthesis of novel agrochemicals, such as pesticides and herbicides. Its chemical properties and reactivity enable the creation of new compounds with enhanced performance and selectivity in controlling pests and weeds.
Used in Drug Discovery:
7-Bromo-5-chloro-1H-indazole is employed as a potential building block in the synthesis of new compounds for drug discovery. Its diverse biological activities and chemical reactivity allow researchers to explore its potential in treating various diseases and conditions, leading to the development of innovative therapeutic agents.
Safety and Handling:
7-Bromo-5-chloro-1H-indazole is typically stored and handled in accordance with standard laboratory procedures for potentially hazardous chemicals. Proper safety measures, such as wearing protective equipment and working in a well-ventilated area, should be followed to minimize risks associated with its use.
Check Digit Verification of cas no
The CAS Registry Mumber 875305-86-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,7,5,3,0 and 5 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 875305-86:
(8*8)+(7*7)+(6*5)+(5*3)+(4*0)+(3*5)+(2*8)+(1*6)=195
195 % 10 = 5
So 875305-86-5 is a valid CAS Registry Number.
InChI:InChI=1/C7H4BrClN2/c8-6-2-5(9)1-4-3-10-11-7(4)6/h1-3H,(H,10,11)
875305-86-5Relevant academic research and scientific papers
Synthesis, antifungal activity and qsar of novel pyrazole amides as succinate dehydrogenase inhibitors
Du, Shijie,Li, Zhonghao,Tian, Zaimin,Xu, Lu
, p. 74 - 85 (2018/01/26)
We design and synthesize a series of novel pyrazole amides based on the commercialized fungicides and our previous work. The antifungal activity was tested in vitro by mycelial growth inhibition assay. The results show that all the compounds are of antifungal activities against the tested fungi at different levels. Among them, N-(2-(7-bromo-5-chloro-1H-indazol-1-yl)phenyl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide (Vk) exhibited higher antifungal activity than boscalid against two fungi. Molecular docking study revealed that the carbonyl oxygen atom of Vk forms two hydrogen bonds toward the hydroxyl hydrogens of TYR58 and TRP173.
Substituted Heterocyclic Ethers and Their Use in CNS Disorders
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Page/Page column 56, (2009/01/24)
The invention encompasses compounds of Formula I, including pharmaceutically acceptable salts, their pharmaceutical compositions, and their use in treating CNS disorders.
