JNJ26854165 (Quisinostat) 2HCl is a chemical compound that functions as a potent and selective inhibitor of histone deacetylase (HDAC) enzymes. It is recognized for its potential in treating various types of cancer and other diseases, such as neurodegenerative disorders. By inhibiting HDAC enzymes, which are crucial in gene expression and protein function regulation, Quisinostat induces cell cycle arrest, promotes apoptosis, and inhibits angiogenesis in cancer cells. The 2HCl form of the compound enhances its stability and solubility, facilitating its application in research and potential clinical uses.
875320-31-3
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Basic information
- Product Name: JNJ26854165(Quisinostat) 2HCl
- Synonyms: JNJ26854165(Quisinostat) 2HCl;JNJ 26481585 dihydrochloride;Quisinostat dihydrochloride;Quisinostat 2HCl;Quisinostat 2HCl, 98%, a new type HDAC inhibitor
- CAS NO:875320-31-3
- Molecular Formula: C21H28Cl2N6O2
- Molecular Weight: 467.39202
- EINECS: N/A
- Product Categories: N/A
- Mol File: 875320-31-3.mol
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: JNJ26854165(Quisinostat) 2HCl(CAS DataBase Reference)
- NIST Chemistry Reference: JNJ26854165(Quisinostat) 2HCl(875320-31-3)
- EPA Substance Registry System: JNJ26854165(Quisinostat) 2HCl(875320-31-3)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 875320-31-3(Hazardous Substances Data)
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875320-31-3 Usage
Uses
Used in Pharmaceutical Industry:JNJ26854165 (Quisinostat) 2HCl is used as an investigational drug for the treatment of cancer. Its application is based on its ability to inhibit HDAC enzymes, leading to cell cycle arrest, apoptosis promotion, and angiogenesis inhibition in cancer cells, which makes it a promising candidate for cancer therapy.
Used in Research Applications:
In the field of scientific research, JNJ26854165 (Quisinostat) 2HCl is used as a tool compound to study the role of HDAC enzymes in gene expression and protein function. Its use aids in understanding the mechanisms of cell cycle regulation, apoptosis, and angiogenesis, contributing to the advancement of cancer treatment strategies.
Used in Neurodegenerative Disorder Treatment:
JNJ26854165 (Quisinostat) 2HCl is also being explored for its potential use in treating neurodegenerative disorders. Its application in this field is due to its ability to modulate the activity of HDAC enzymes, which may have implications for the progression and management of such disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 875320-31-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,7,5,3,2 and 0 respectively; the second part has 2 digits, 3 and 1 respectively.Calculate Digit Verification of CAS Registry Number 875320-31:
(8*8)+(7*7)+(6*5)+(5*3)+(4*2)+(3*0)+(2*3)+(1*1)=173
173 % 10 = 3
So 875320-31-3 is a valid CAS Registry Number.
875320-31-3Upstream product
875320-31-3Downstream Products
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JNJ26854165(Quisinostat) 2HCl
