875327-52-9Relevant academic research and scientific papers
Protected mercaptoalkylpyrimidinones: Synthesis and test for immunostimulating activity
Briel,Droessler,Rybak,Holzer,Dobner
, p. 415 - 417 (2007/10/03)
3-Hydroxyalkyl-pyrimidine 1 reacts with phosphoroxychloride and thioglycolic acid or thiourea to yield pyrimidin-3-ylalkylthioacetic acids 3 or pyrimidin-3-ylalkylthiouroniumsalts 5 respectively. Some of the pyrimidines 3 and 5 showed immunomodulatory activity.
