875415-08-0Relevant academic research and scientific papers
Identification of highly efficacious glucocorticoid receptor agonists with a potential for reduced clinical bone side effects
Harcken, Christian,Riether, Doris,Kuzmich, Daniel,Liu, Pingrong,Betageri, Raj,Ralph, Mark,Emmanuel, Michel,Reeves, Jonathan T.,Berry, Angela,Souza, Donald,Nelson, Richard M.,Kukulka, Alison,Fadra, Tazmeen N.,Zuvela-Jelaska, Ljiljana,Dinallo, Roger,Bentzien, J?rg,Nabozny, Gerald H.,Thomson, David S.
, p. 1583 - 1598 (2014/03/21)
Synthesis and structure-activity relationship (SAR) of a series of nonsteroidal glucocorticoid receptor (GR) agonists are described. These compounds contain "diazaindole" moieties and display different transcriptional regulatory profiles in vitro and are
