875489-16-0Relevant academic research and scientific papers
Pharmacokinetics and metabolism studies on (3-tert-butyl-7-(5- methylisoxazol-3-yl)-2-(1-methyl-1H-1,2,4-triazol-5-ylmethoxy) pyrazolo[1,5-d][1,2,4]triazine, a functionally selective GABAA α5 inverse agonist for cognitive dysfunction
Jones, Philip,Atack, John R.,Braun, Matthew P.,Cato, Brian P.,Chambers, Mark S.,O'Connor, Desmond,Cook, Susan M.,Hobbs, Sarah C.,Maxey, Robert,Szekeres, Helen J.,Szeto, Nicola,Wafford, Keith A.,MacLeod, Angus M.
, p. 872 - 875 (2006)
(3-tert-Butyl-7-(5-methylisoxazol-3-yl)-2-(1-methyl-1H-1,2, 4-triazol-5-ylmethoxy)pyrazolo[1,5-d][1,2,4]triazine (1) was recently identified as a functionally selective, inverse agonist at the benzodiazepine site of GABAA α5 receptors and enhan
