875489-16-0

Basic information

• Product Name: 1H-Pyrazole-3-carboxylic acid, 4-(1,1-dimethylethyl)-5-[[(4-methylphenyl)sulfonyl]oxy]-
• CAS NO: 875489-16-0
• Molecular Formula: C15H18N2O5S
• Molecular Weight: 338.384
• Mol File: 875489-16-0.mol

Chemical Properties

• CAS DataBase Reference: 1H-Pyrazole-3-carboxylic acid, 4-(1,1-dimethylethyl)-5-[[(4-methylphenyl)sulfonyl]oxy]-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrazole-3-carboxylic acid, 4-(1,1-dimethylethyl)-5-[[(4-methylphenyl)sulfonyl]oxy]-(875489-16-0)
• EPA Substance Registry System: 1H-Pyrazole-3-carboxylic acid, 4-(1,1-dimethylethyl)-5-[[(4-methylphenyl)sulfonyl]oxy]-(875489-16-0)

Safety Data

• Hazardous Substances Data: 875489-16-0(Hazardous Substances Data)

Upstream product

• 265643-79-6 4-tert-Butyl-5-formyl-3-[(4-methylphenyl)sulphonyloxy]pyrazole 

Downstream Products

• 875498-37-6 toluene-4-sulfonic acid 3-tert-butyl-7-(5-methyl-isoxazol-3-yl)-4-oxo-4,5-dihydro-pyrazolo[1,5-d][1,2,4]triazin-2-yl ester 
• 875489-17-1 toluene-4-sulfonic acid 4-tert-butyl-5-[N'-(5-methyl-isoxazole-3-carbonyl)-hydrazinocarbonyl]-1H-pyrazol-3-yl ester 

Relevant articles and documents

Pharmacokinetics and metabolism studies on (3-tert-butyl-7-(5- methylisoxazol-3-yl)-2-(1-methyl-1H-1,2,4-triazol-5-ylmethoxy) pyrazolo[1,5-d][1,2,4]triazine, a functionally selective GABAA α5 inverse agonist for cognitive dysfunction

(3-tert-Butyl-7-(5-methylisoxazol-3-yl)-2-(1-methyl-1H-1,2, 4-triazol-5-ylmethoxy)pyrazolo[1,5-d][1,2,4]triazine (1) was recently identified as a functionally selective, inverse agonist at the benzodiazepine site of GABAA α5 receptors and enhan