875551-28-3

Basic information

• Product Name: 2'-(chloroMethyl)-4-fluoro-5-isopropyl-2-Methoxy-4'-(trifluoroMethyl)-1,1'-biphenyl
• Synonyms: 2'-(chloroMethyl)-4-fluoro-5-isopropyl-2-Methoxy-4'-(trifluoroMethyl)-1,1'-biphenyl;2'-(Chloromethyl)-4-fluoro-2-methoxy-5-(1-methylethyl)-4'-(trifluoromethyl)-1,1'-biphenyl;Anacetrapib Intermediate I;1-[2-(chloromethyl)-4-(trifluoromethyl)phenyl]-4-fluoro-2-methoxy-5-(propan-2-yl)benzene;2'-Chloromethyl-4-fluoro-5-isopropyl-2-methoxy-4'-trifluoromethylbiphenyl;EOS-61121;Anacetrapib Intermediate 3
• CAS NO: 875551-28-3
• Molecular Formula: C18H17ClF4O
• Molecular Weight: 360.7735928
• Product Categories: Anacetrapib;MK 0859
• Mol File: 875551-28-3.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2'-(chloroMethyl)-4-fluoro-5-isopropyl-2-Methoxy-4'-(trifluoroMethyl)-1,1'-biphenyl(CAS DataBase Reference)
• NIST Chemistry Reference: 2'-(chloroMethyl)-4-fluoro-5-isopropyl-2-Methoxy-4'-(trifluoroMethyl)-1,1'-biphenyl(875551-28-3)
• EPA Substance Registry System: 2'-(chloroMethyl)-4-fluoro-5-isopropyl-2-Methoxy-4'-(trifluoroMethyl)-1,1'-biphenyl(875551-28-3)

Safety Data

• Hazardous Substances Data: 875551-28-3(Hazardous Substances Data)

Usage

General Description

2'-(ChloroMethyl)-4-fluoro-5-isopropyl-2-Methoxy-4'-(trifluoroMethyl)-1,1'-biphenyl is a chemical compound that belongs to the biphenyl class of compounds. It contains a chloromethyl group, a fluoro group, an isopropyl group, a methoxy group, and a trifluoromethyl group. 2'-(chloroMethyl)-4-fluoro-5-isopropyl-2-Methoxy-4'-(trifluoroMethyl)-1,1'-biphenyl has potential applications in the field of pharmaceuticals, agrochemicals, and materials science due to its unique structure and properties. Its synthesis and characterization are of interest to researchers for developing new materials and compounds for various industrial applications. Additionally, its potential reactivity and biological activity make it an intriguing target for further study in the chemical and pharmaceutical industries.

Upstream product

• 1383814-85-4 (4'-fluoro-2'-methoxy-5'-(prop-1-en-2-yl)-4-(trifluoromethyl)biphenyl-2-yl)methanol 
• 958029-47-5 2-[4'-fluoro-2'-methoxy-5'-(propan-2-yl)-4-(trifluoromethyl)biphenyl-2-yl]-4,5-dihydro-1,3-oxazole 
• 368-77-4 3-trifluoromethylbenzonitrile 
• 851513-74-1 2-(3-(trifluoromethyl)phenyl)-4,5-dihydrooxazole 
• 1383676-72-9 C₁₀H₁₂BrFMgO 
• 875446-55-2 2-fluoro-4-methoxy-1-(prop-1-en-2-yl)benzene 
• 1383814-83-2 4-fluoro-2-methoxy-5-(2-propenyl)phenylboronic acid 
• 1383814-82-1 1-bromo-4-fluoro-2-methoxy-5-(1-methylvinyl)benzene 
• 958029-46-4 2-(5-bromo-2-fluoro-4-methoxyphenyl)propan-2-ol 
• 914221-54-8 1-(5-bromo-2-fluoro-4-methoxyphenyl)ethan-1-one 
• 450-88-4 1-bromo-4-fluoro-2-methoxybenzene 
• 348-57-2 2,4-difluorobromobenzene 
• 944317-92-4 1-bromo-4-fluoro-2-methoxy-5-(propan-2-yl)-benzene 
• 1262414-96-9 2-(2-fluoro-4-methoxyphenyl)isopropane 

Relevant articles and documents

Process for a CETP Inhibitor

An efficient process is disclosed for producing the compound of formula I, which is the CETP inhibitor anacetrapib, which raises HDL-cholesterol and reduces LDL-cholesterol in human patients and may be effective for treating or reducing the risk of developing atherosclerosis:

PROCESS FOR A CETP INHIBITOR

An efficient process is disclosed for producing the compound of formula I, which is the CETP inhibitor anacetrapib, which raises HDL-cholesterol and reduces LDL-cholesterol in human patients and may be effective for treating or reducing the risk of developing atherosclerosis:.

Synthesis of intermediates for preparing anacetrapib and derivates thereof

The present invention relates to the field of organic chemistry, more specifically to the synthesis of intermediate compounds which can be used in the synthesis of pharmaceutically active agents such as anacetrapib or derivatives thereof.