875558-46-6

Upstream product

• 454-78-4 3-bromo-4-chlorobenzotrifluoride 
• 1066-54-2 trimethylsilylacetylene 

Downstream Products

• 148258-96-2 (Z)-4-(2-Chloro-5-trifluoromethyl-phenyl)-1,1,1-trifluoro-2-trifluoromethyl-but-3-en-2-ol 
• 148258-95-1 3-Hydroxy-3-trifluoromethyl-1-(2-chloro-5-trifluoromethylphenyl)-4,4,4-trifluorobut-1-yne 
• 148258-94-0 1-chloro-2-ethynyl-4-(trifluoromethyl)benzene 

Relevant academic research and scientific papers

THE SYNTHESIS OF 2,2-BIS(TRIFLUOROMETHYL)BENZOPYRAN DERIVATIVES: A NEW ROUTE TO AN IMPORTANT CLASS OF POTASSIUM CHANNEL ACTIVATORS

A new route to an important class of biologically active benzopyrans was developed via an intramolecular cyclisation and cis diol formation. Key Words: Benzopyran; intramolecular cyclisation; potassium channel activator

SUBSTITUTED PYRAZOLES, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE

The present invention relates to substituted pyrazoles, compositions containing such compounds and methods of treatment. The compounds are glucagon receptor antagonists and thus are useful for treating, preventing or delaying the onset of type 2 diabetes