875653-25-1

Upstream product

• 24964-64-5 3-Cyanobenzaldehyde 
• 343338-28-3 (S)-2-methylpropane-2-sulfinamide 

Downstream Products

• 1286182-92-0 2-methyl-propane-2-sulfinic acid [(R)-1-(3-cyano-phenyl)ethyl]amide 
• 1286182-87-3 2-pyridin-2-yl-pyrimidine-5-carboxylic acid ((R)-1-{3-[5-(1-hydroxy-1-methyl-ethyl)-1,2,4-oxadiazol-3-yl]phenyl}ethyl)amide 
• 1286693-23-9 3-[(1R)-1-aminoethyl]benzonitrile hydrochloride 
• 1286182-94-2 2-pyridin-2-yl-pyrimidine-5-carboxylic acid [(R)-1-(3-cyano-phenyl)ethyl]amide 
• 1286182-95-3 2-pyridin-2-yl-pyrimidine-5-carboxylic acid {(R)-1-[3-(N-hydroxycarbamimidoyl)phenyl]ethyl}amide 

Relevant academic research and scientific papers

MODULATORS OF TREX1

Provided are compounds of Formula (I): and pharmaceutically acceptable salts and compositons thereof, which are useful for treating a variety of conditions associated with TREX1.

PHENYLOXADIAZOLE DERIVATIVES AS PGDS INHIBITORS

This invention is directed to a compound of formula (I): wherein R1, R2 and R3 are as defined herein, a pharmaceutical composition comprising the compound, intermediates and processes for making said compounds, and the use of the compound to treat allergi