875757-74-7Relevant academic research and scientific papers
Pyrazolopyrimidines and pyrazolotriazines with potent activity against herpesviruses
Gudmundsson, Kristjan S.,Johns, Brian A.,Weatherhead, Jason
scheme or table, p. 5689 - 5692 (2010/04/05)
Synthesis of several pyrazolo[1,5-c]pyrimidines, pyrazolo[1,5-a]pyrimidines and pyrazolo[1,5-a][1,3,5]triazines with potent activity against herpes simplex viruses is described. Synthetic approaches allowing for variation of the substitution pattern are o
Synthesis of novel 4-(2-amino-5-thiazolyl)-pyrimidine-2-amines as potential protein kinase inhibitors
Susnik, Marko P.,Schnuerch, Michael,Mihovilovic, Marko D.,Mereiter, Kurt,Stanetty, Peter
experimental part, p. 423 - 430 (2010/05/01)
A short and efficient sequence for the synthesis of a series of 4-(2-amino-5-thiazolyl)-pyrimidine-2-amines was developed. 1-Phenyl-2-(6- pyrimidinyl)-ethanones, obtained via Weinreb's methodology, were used in a Hantzsch thiazole cyclization reaction, followed by introduction of the aniline moieties via nucleophilic substitution.
HETEROCYCLIC COMPOUNDS
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Page/Page column 45, (2008/06/13)
New compounds of formula (I), wherein the meanings for the various substituents are as disclosed in the description. These compounds are useful as p38 kinase inhibitors.
