875757-74-7Relevant academic research and scientific papers
Synthesis of novel 4-(2-amino-5-thiazolyl)-pyrimidine-2-amines as potential protein kinase inhibitors
Susnik, Marko P.,Schnuerch, Michael,Mihovilovic, Marko D.,Mereiter, Kurt,Stanetty, Peter
experimental part, p. 423 - 430 (2010/05/01)
A short and efficient sequence for the synthesis of a series of 4-(2-amino-5-thiazolyl)-pyrimidine-2-amines was developed. 1-Phenyl-2-(6- pyrimidinyl)-ethanones, obtained via Weinreb's methodology, were used in a Hantzsch thiazole cyclization reaction, followed by introduction of the aniline moieties via nucleophilic substitution.
Pyrazolopyrimidines and pyrazolotriazines with potent activity against herpesviruses
Gudmundsson, Kristjan S.,Johns, Brian A.,Weatherhead, Jason
scheme or table, p. 5689 - 5692 (2010/04/05)
Synthesis of several pyrazolo[1,5-c]pyrimidines, pyrazolo[1,5-a]pyrimidines and pyrazolo[1,5-a][1,3,5]triazines with potent activity against herpes simplex viruses is described. Synthetic approaches allowing for variation of the substitution pattern are o
HETEROCYCLIC COMPOUNDS
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Page/Page column 45, (2008/06/13)
New compounds of formula (I), wherein the meanings for the various substituents are as disclosed in the description. These compounds are useful as p38 kinase inhibitors.
