875768-16-4Relevant academic research and scientific papers
Gold-catalyzed stereoselective synthesis of azacyclic compounds through a redox/[2 + 2 + 1] cycloaddition cascade of nitroalkyne substrates
Jadhav, Appaso Mahadev,Bhunia, Sabyasachi,Liao, Hsin-Yi,Liu, Rai-Shung
supporting information; experimental part, p. 1769 - 1771 (2011/04/15)
We report a new redox/cycloaddition cascade on readily available 1-alkynyl-2-nitrobenzenes that produces complex azacyclic compounds stereoselectively. The core structures of the resulting products are constructed through a formal [2 + 2 + 1] cycloaddition among α-carbonyl carbenoids, nitroso species, and external alkenes.
COMPOUNDS USEFUL FOR INHIBITING CHK1
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Page/Page column 41, (2008/06/13)
Substituted urea compounds useful in the treatment of diseases and conditions related to DNA damage or lesions in DNA replication are disclosed. Methods of making the compounds, and their use as ther-apeutic agents, for example, in treating cancer and oth
