875779-49-0Relevant academic research and scientific papers
1,4- DIHYDROPYRIDINE DERIVATIVES WITH HSP MODULATING ACTIVITY
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Page/Page column 27, (2013/06/06)
The invention provides 1,4-dihydropyridine derivatives of formula (I) wherein R1 is optionally substituted C6-24aryl group or 5 to 6 membered heteroaryl group comprising 1 to 3 nitrogen atoms or other heteroatoms like oxygen and sulp
Study of 1,4-dihydropyridine structural scaffold: Discovery of novel sirtuin activators and inhibitors
Mai, Antonello,Valente, Sergio,Meade, Sarah,Carafa, Vincenzo,Tardugno, Maria,Nebbioso, Angela,Galmozzi, Andrea,Mitro, Nico,De Fabiani, Emma,Altucci, Lucia,Kazantsev, Aleksey
experimental part, p. 5496 - 5504 (2010/04/26)
NAD+-dependent sirtuin deacetylases have emerged as potential therapeutic targets for treatment of human illnesses such as cancer, metabolic, cardiovascular, and neurodegenerative diseases. The benefits of sirtuin modulation by small molecules
