875798-98-4

Upstream product

• 221344-09-8 (1S,2S,4R,5S)-4,5-Dihydroxy-cyclohexane-1,2-dicarboxylic acid di-tert-butyl ester 

Downstream Products

• 875801-22-2 4-[5-acetoxy-6-acetoxymethyl-3-acetylamino-4-(3,4,5-triacetoxy-6-acetoxymethyl-tetrahydro-pyran-2-yloxy)-tetrahydro-pyran-2-yloxy]-5-(1-benzyloxycarbonyl-2-cyclohexyl-ethoxy)-cyclohexane-1,2-dicarboxylic acid di-tert-butyl ester 

Relevant academic research and scientific papers

Ganglioside GM1 mimics: Lipophilic substituents improve affinity for cholera toxin

Ganglioside GM1 mimics including (R)-2-hydroxy-3-cyclohexylpropionic acid or (R)-2-hydroxy-3-phenylpropionic acid as replacements for NeuAc are stronger cholera toxin binders than the parent ligand 2, which includes (R)-2-hydroxy-propionic acid.

Intramolecular carbohydrate-aromatic interaction and intermolecular van der Waals interactions enhance the molecular recognition ability of GM1 glycomimetics for cholera toxin

The design and synthesis of two GM1 glycomimetics, 6 and 7, and analysis of their conformation in the free state and when complexed to cholera toxin is described. These compounds, which include an (R)-cyclohexyllactic acid and an (R)-phenyllactic acid fra