87580-06-1

Upstream product

• 100-44-7 benzyl chloride 
• 184777-79-5 2-hydroxyimino-3-(2-benzyloxy-3,5-dibromo-4-methoxyphenyl)propionic acid 

Downstream Products

• 87580-07-2 methyl 2-hydroxyimino-3-(3,5-dibromo-2-hydroxy-4-methoxyphenyl)propionate 
• 184777-86-4 methyl 2-benzyloxyimino-3-(2'-benzyloxy-3,5-dibromo-4-methoxyphenyl)propionate 
• 28687-76-5 N,N'-bis<3-(3,5-dibromo-2-hydroxy-4-methoxyphenyl)-2-hydroxyiminopropionyl>-1,4-butanediamine 

Relevant academic research and scientific papers

TOTAL SYNTHESES OF (+/-)-AEROTHIONIN AND (+/-)-HOMOAEROTHIONIN

Both aerothionin and homoaerothionin, the novel metabolites of the sponges Aplysina aerophoba, A. fistularis and Verongia thiona, have been synthesized in racemic form.

Total syntheses of (±)-aerothionin, (±)-homoaerothionin, and (±)-aerophobin-1

(±)-Aerothionin, (±)-homoaerothionin, and (±)-aerophobin-1 have been successfully synthesized using phenolic oxidation of the methyl pyruvate oxime derivative with thallium(III) trifluoroacetate as a key step. The stereostructure of aerophobin-2 has been also established by comparison of the 1H NMR spectrum with those of related compounds.