875801-90-4Relevant academic research and scientific papers
Synthesis and pharmacological evaluation of novel substituted 9-deazaxanthines as A2B receptor antagonists
Nieto, Mara Isabel,Balo, Mara Carmen,Brea, Jos,Caamao, Olga,Fernndez, Franco,Garca-Mera, Xerardo,Lpez, Carmen,Loza, Mara Isabel,Rodrguez-Borges, Jos Enrique,Vidal, Bernat
experimental part, p. 2884 - 2892 (2010/08/20)
A new series of 9-deazaxanthine derivatives with various substituents at the heterocyclic system were synthesized and evaluated for their binding affinities for the four human recombinant adenosine receptors, A 1A3 subtypes. A number
Design, synthesis, and structure-activity relationships of 1-,3-,8-, and 9-substituted-9-deazaxanthines at the human A2B adenosine receptor
Carotti, Angelo,Cadavid, Maria Isabel,Centeno, Nuria B.,Esteve, Cristina,Loza, Maria Isabel,Martinez, Ana,Nieto, Rosa,Ravi?a, Enrique,Sanz, Ferran,Segarra, Victor,Sotelo, Eddy,Stefanachi, Angela,Vidal, Bernat
, p. 282 - 299 (2007/10/03)
Over two hundred 1-, 3-, 8-, and 9-substituted-9-deazaxanthines were prepared and evaluated for their binding affinity at the recombinant human adenosine receptors, in particular at the hA2B and hA2A subtypes. Several ligands endowed
