875898-85-4 Usage
General Description
2,2-difluoro-2-(4-methylphenyl)acetamide is a chemical compound with the molecular formula C10H11F2NO. It is a fluoroalkyl compound and a derivative of acetamide, which is commonly used in organic synthesis and pharmaceutical research. This chemical is characterized by the presence of two fluorine atoms and a methylphenyl group attached to the acetamide molecule. It has potential applications in medicinal chemistry and drug development due to its unique structure and pharmacological properties. Additionally, it may also be used as a building block in the synthesis of various organic compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 875898-85-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,7,5,8,9 and 8 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 875898-85:
(8*8)+(7*7)+(6*5)+(5*8)+(4*9)+(3*8)+(2*8)+(1*5)=264
264 % 10 = 4
So 875898-85-4 is a valid CAS Registry Number.
875898-85-4Relevant academic research and scientific papers
Direct Approach to 3-Fluoroindoles and 3,3-Difluoroindolines from 2,2-Difluoro-2-phenylethan-1-amines via C-H/N-H Coupling
Zhang, Lanfei,Zhang, Xiaofei,Cui, Yongmei,Yang, Chunhao
supporting information, p. 3815 - 3826 (2021/06/28)
Herein, a direct method for the synthesis of 3-fluoroindoles and 3,3-difluoroindolines from easily accessible 2,2-difluoro-2-phenyl ethan-1-amines is presented. This protocol was performed by Pd-catalyzed direct C-H/N-H coupling and employed picolinamide as a directing group. By controlling the temperature for this transformation, various 3,3-difluoroindolines and 3-fluoroindoles could be isolated with moderate to good yields.
1,3-DISUBSTITUTED HETEROARYL NMDA/NR2B ANTAGONISTS
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Page/Page column 70-71, (2010/10/20)
Compounds represented by Formula I: (wherein A, B, D, P, Q, R1, R2, R3, W and Y are described herein) or pharmaceutically acceptable salts thereof, are effective as NMDA/NR2B antagonists useful for treating neurological co
