87598-76-3

Upstream product

• 16900-53-1 3-bromopropiolic acid 
• 100-51-6 benzyl alcohol 
• 14447-01-9 benzyl prop-2-ynoate 

Downstream Products

• 87598-78-5 3-bromo-2-(carbobenzyloxy)bicyclo<2.2.2>octadiene 
• 87598-81-0 3-bromo-1-<(tert-butyldimethylsilyl)oxy>-2-(carbobenzyloxy)-6-methylbicyclo<2.2.2>octadiene 
• 1609632-92-9 benzyl 3,3-bis(N-(3-(3-nitrophenyl)prop-2-ynyl)-4-methylphenylsulfonamido)acrylate 
• 1609632-91-8 benzyl 3,3-bis(N-(3-phenylprop-2-ynyl)-4-methylphenylsulfonamido)acrylate 
• 1609632-93-0 benzyl 3,3-bis(N-(3-(4-bromophenyl)prop-2-ynyl)methylsulfonamido)acrylate 
• 87678-47-5 6-{(3S,4S,5S,7S)-7-[(2R,3R,5R)-5-Ethyl-5-((2S,5S,6R)-5-ethyl-5-hydroxy-6-methyl-tetrahydro-pyran-2-yl)-3-methyl-tetrahydro-furan-2-yl]-4-hydroxy-3,5-dimethyl-6-oxo-nonyl}-2-hydroxy-3-methyl-benzoic acid benzyl ester 
• 87678-49-7 6-{(3S,4R,5S,7S)-7-[(2R,3R,5R)-5-Ethyl-5-((2S,5S,6R)-5-ethyl-5-hydroxy-6-methyl-tetrahydro-pyran-2-yl)-3-methyl-tetrahydro-furan-2-yl]-4-hydroxy-3,5-dimethyl-6-oxo-nonyl}-2-hydroxy-3-methyl-benzoic acid benzyl ester 
• 87678-45-3 6-{(3S,4S,5R,7S)-7-[(2R,3R,5R)-5-Ethyl-5-((2S,5S,6R)-5-ethyl-5-hydroxy-6-methyl-tetrahydro-pyran-2-yl)-3-methyl-tetrahydro-furan-2-yl]-4-hydroxy-3,5-dimethyl-6-oxo-nonyl}-2-hydroxy-3-methyl-benzoic acid benzyl ester 
• 87678-44-2 ent-benzyl lasalocid A 
• 87598-83-2 1-<(tert-butyldimethylsilyl)oxy>-2-(carbobenzyloxy)-6-methyl-3-<3(S)-methyl-4-pentenyl>bicyclo<2.2.2>octadiene 
• 75371-90-3 benzyl 2-hydroxy-3-methyl-6-<4,5-dihydroxy-3(S)-methylpentyl>benzoate 
• 87598-75-2 benzyl 2-hydroxy-3-methyl-6-<3(S)-formylbutyl>benzoate 

Relevant academic research and scientific papers

Direct spirocyclization from keto-sulfonamides: An approach to azaspiro compounds

Spontaneous spirocyclization of keto-sulfonamides via ynamides through a one-pot process is presented. Push-pull ynamides were obtained through Michael addition/elimination without Cu. The obtained azaspiro compounds are building blocks for indole alkaloids. Theoretical studies provide insights into the mechanism of the formal Conia-ene reaction.

Total Synthesis of Polyether Antibiotics. Synthesis of the Enantiomer of Lasalocid A (X-537A)

A convergent total synthesis of the enantiomer of lasalocid A (X-537A) and the preliminary results of the biological testing of this compound are reported.