876069-78-2

Upstream product

• 317842-43-6 N-(2,2-dimethoxyethyl)-4-methyl-N-(prop-2-yn-1-yl)benzenesulfonamide 
• 876069-60-2 N-(2,2-bis-ethylsulfanyl-ethyl)-4-methyl-N-prop-2-ynyl-benzenesulfonamide 

Relevant academic research and scientific papers

Mercuric chloride and iodide mediated cyclization of tethered alkynedithioacetals as a general route to five- and six-membered rings: Tuning of regioselectivity by alkyne substitution

Mercuric chloride mediated cyclization of tethered alkynedithioacetals has been established as a general route to five- and six-membered carbocycles and heterocycles. Substitution at the alkyne terminus leads to preferential formation of five-membered rings, whereas unsubstituted alkynedithioacetals give six-membered rings as the major products. Mercuric iodide interrupts the reaction at the intermediate dithioacetal stage.