87617-29-6

Basic information

• Product Name: 2-AMINO-5-ISOPROPYLBENZOTRIFLUORIDE
• Synonyms: 2-AMINO-5-ISOPROPYLBENZOTRIFLUORIDE;4-ISOPROPYL-2-(TRIFLUOROMETHYL);4-ISOPROPYL-2-(TRIFLUOROMETHYL)ANILINE;4-ISOPROPYL-2-TRIFLUOROMETHYL-PHENYLAMINE;2-Amino-5-isopropylbenzotrifluoride, 97+%
• CAS NO: 87617-29-6
• Molecular Formula: C10H12F3N
• Molecular Weight: 203.2
• Mol File: 87617-29-6.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 220.6°C at 760 mmHg
• Flash Point: 93.1°C
• Appearance: /
• Density: 1,158 g/cm3
• Vapor Pressure: 0.112mmHg at 25°C
• Refractive Index: 1.4820
• Sensitive: Light Sensitive
• CAS DataBase Reference: 2-AMINO-5-ISOPROPYLBENZOTRIFLUORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMINO-5-ISOPROPYLBENZOTRIFLUORIDE(87617-29-6)
• EPA Substance Registry System: 2-AMINO-5-ISOPROPYLBENZOTRIFLUORIDE(87617-29-6)

Safety Data

• Statements: 20/21/22
• Safety Statements: 24/25-36/37/39
• Hazardous Substances Data: 87617-29-6(Hazardous Substances Data)

Usage

General Description

2-Amino-5-isopropylbenzotrifluoride is a chemical compound with the molecular formula C10H12F3N. It is a colorless liquid that is used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. 2-AMINO-5-ISOPROPYLBENZOTRIFLUORIDE is known for its use as a building block in the production of various drugs and pesticide products. Its structure consists of an aromatic benzene ring with a trifluoromethyl group and an isopropylamine substituent. Due to its versatile reactivity and stability, 2-Amino-5-isopropylbenzotrifluoride is a valuable compound in the field of organic chemistry and drug development.

InChI:InChI=1/C10H12F3N/c1-6(2)7-3-4-9(14)8(5-7)10(11,12)13/h3-6H,14H2,1-2H3

Upstream product

• 887144-94-7 Togni's reagent II 
• 99-88-7 4-Isopropylaniline 

Relevant articles and documents

Transition metal-free direct C–H trifluoromethyltion of (hetero)arenes with Togni's reagent

A new transition-metal-free direct C–H trifluoromethylation reaction of (hetero)arenes with Togni's reagent was developed. This transformation proceeded smoothly under mild conditions and exhibited good tolerance of many synthetically relevant functional groups. It provided an alternative approach for the synthesis of trifluoromethylated (hetero)arenes.

Nickel-Catalyzed Direct C-H Trifluoromethylation of Free Anilines with Togni's Reagent

An efficient nickel-catalyzed C-H trifluoromethylation for the synthesis of trifluoromethylated free anilines using Togni's reagent has been developed. This approach exhibits a good functional group tolerance, good regioselectivity, and chemoselectivity under mild conditions. The newly developed economical one-step method is a better alternative to synthesize trifluoromethylated free anilines.