876179-80-5Relevant academic research and scientific papers
Rapid synthesis of 1,3,5-substituted 1,2,4-triazoles from carboxylic acids, amidines, and hydrazines
Castanedo, Georgette M.,Seng, Pamela S.,Blaquiere, Nicole,Trapp, Sean,Staben, Steven T.
scheme or table, p. 1177 - 1179 (2011/04/16)
A general method for the synthesis of 1,3,5-trisubstituted 1,2,4-triazoles has been developed from reaction of carboxylic acids, primary amidines, and monosubstituted hydrazines. This highly regioselective and one-pot process provides rapid access to highly diverse triazoles.
