87628-27-1

Usage

Molecular structure

The compound contains a pyrazolo[4,3-c]pyridine ring system with an acetyl group at position 5 and a 4-chlorophenyl group at position 3.

Tetrahydro structure

The compound has a tetrahydro structure with four additional carbon atoms in the ring system.

Bioactivity

The specific structure of the compound makes it of interest for bioactivity studies and potential drug development.

Upstream product

• 144507-33-5 1-[5-(4-Chloro-benzoyl)-4-morpholin-4-yl-3,6-dihydro-2H-pyridin-1-yl]-ethanone 
• 55459-60-4 1-(4-(morpholin-4-yl)-3,6-dihydro-2H-pyridin-1-yl)ethanone 
• 32161-06-1 1-acetyl-4-piperidinone 
• 144507-32-4 N-acetyl-3-(4-chlorobenzoyl)-4-piperidone 

Downstream Products

• 400797-66-2 1-[3-(4-chlorophenyl)-1-oxiranylmethyl-1,4,6,7-tetrahydropyrazolo[4,3-c]pyridin-5-yl]ethanone 
• 400802-42-8 1-(3-(4-Chloro-phenyl)-1-{3-[4-(2-fluoro-phenyl)-piperazin-1-yl]-propyl}-1,4,6,7-tetrahydro-pyrazolo[4,3-c]pyridin-5-yl)-ethanone 
• 400802-88-2 1-[3-(4-Chloro-phenyl)-1-(3-chloro-propyl)-1,4,6,7-tetrahydro-pyrazolo[4,3-c]pyridin-5-yl]-ethanone 
• 95936-15-5 3-(4-Chloro-phenyl)-1-methyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine; hydrochloride 
• 87628-75-9 1-[3-(4-Chloro-phenyl)-1-methyl-1,4,6,7-tetrahydro-pyrazolo[4,3-c]pyridin-5-yl]-ethanone 
• 95936-12-2 3-(4-Chloro-phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine; hydrochloride 

Relevant academic research and scientific papers

Indanyl-Substituted 4,5,6,7-Tetrahydro-1H-Pyrazolo[4,3-C]Pyridines, Their Use as Medicament, and Pharmaceutical Preparations Comprising Them

The invention relates to substituted 4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridines of formula (I), their use as medicament, and pharmaceutical preparations comprising them. The compounds of formula (I) act on the TASK-1 potassium channel. The compounds are particularly suitable for the treatment or prevention of atrial arrhythmias, for example atrial fibrillation (AF) or atrial flutter.

INDANYL-SUBSTITUTED 4,5,6,7-TETRAHYDRO-1H-PYRAZOLO[4,3-C]PYRIDINES, THEIR USE AS MEDICAMENT, AND PHARMACEUTICAL PREPARATIONS COMPRISING THEM

The invention relates to substituted 4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridines of formula (I), their use as medicament, and pharmaceutical preparations comprising them. The compounds of formula I act on the TASK-1 potassium channel. The compounds are suitable for the treatment or prevention of atrial arrhythmias, for example atrial fibrillation (AF) or atrial flutter.

INDANYL-SUBSTITUTED 4,5,6,7-TETRAHYDRO-1H-PYRAZOLO[4,3-C]PYRIDINES, THEIR USE AS MEDICAMENT, AND PHARMACEUTICAL PREPARATIONS COMPRISING THEM

The invention relates to substituted 4,5,6,7-tetrahydro-1 H-pyrazolo[4,3-c]pyridines of formula (I), their use as medicament, and pharmaceutical preparations comprising them. The compounds of formula (I) act on the TASK-1 potassium channel. The compounds are particularly suitable for the treatment or prevention of atrial arrhythmias, for example atrial fibrillation (AF) or atrial flutter.

Method for treating allergies using substituted pyrazoles

A method for treating an allergic condition, including an atopic allergic condition, using substituted pyrazoles.

Nonpeptidic, noncovalent inhibitors of the cysteine protease cathepsin S

The first nonpeptidic, noncovalent inhibitors of the cysteine protease cathepsin S (CatS) are described. Electronic database searching using the program DOCK generated a screening set of potential CatS inhibitors from which two lead structures were identi

Method for treating allergies using substituted pyrazoles

A method for treating an allergic condition, including an atopic allergic condition, using substituted pyrazoles.

Method for treating allergies using substituted pyrazoles

A method for treating an allergic condition, including an atopic allergic condition, using substituted pyrazoles.

Synthesis, in Vitro 3H>Prazosin Displacement, and in Vivo Activity of 3-Aryl-4,5,6,7-tetrahydropyrazolopyridines, a New Class of Antihypertensive Agents

A series of a new 3-aryl-4,5,6,7-tetrahydropyrazolopyridines was synthesized and screened for in vitro 3H>prazosin displacement activity.The results correlated well with their antihypertensive activity in spontaneous hypertensive rats.