876343-33-8

Usage

Structure

A compound consisting of a pyridine ring attached to a methylpiperazine group.

Common Uses

Used as an intermediate in the synthesis of pharmaceuticals and other organic compounds.

Biological Activity

Known to have biological activity and is used in the development of drugs targeting the central nervous system and other diseases.

Potential Uses

May have potential uses in research settings for its interactions with various biological targets.

Handling Precautions

It may pose health risks if not used and handled properly, so it is important to handle 2-(4-Methylpiperazin-1-yl)pyridin-4-aMine with caution.

Upstream product

• 109-01-3 1-methyl-piperazine 
• 7598-35-8 2-bromo-4-aminopyridine 
• 876343-35-0 1-methyl-4-(4-nitropyridin-2-yl)-piperazine 
• 14432-12-3 4-Amino-2-chloropyridine 

Downstream Products

• 1007206-02-1 4-(3-Methoxy-phenyl)-7-[2-(4-methyl-piperazin-1-yl)-pyridin-4-yl]-2-morpholin-4-yl-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidine 

Relevant academic research and scientific papers

NEW BENZAMIDE DERIVATIVES AS PPAR-GAMMA MODULATORS

The present invention relates to novel benzamides derivatives of formula (I) as modulators of PPAR-gamma receptor, to processes for their preparation, to pharmaceutical compositions comprising said compounds and to said compound for use in the treatment of pathological conditions, disorders or diseases that can improve by modulation of PPAR-gamma receptor, such as cancer; metabolic diseases, inflammatory diseases, respiratory disorders, autoimmune diseases, neurodegenerative diseases, cardiovascular diseases and renal diseases.

NOVEL AMINOMETHYL-PHENOL DERIVATIVES AS ANTIMALARIAL AGENTS

The invention relates to novel aminomethyl-phenol derivatives of formula I wherein R1 to R4, X, A and B are as defined for formula I and their use as active ingredients in the preparation of pharmaceutical compositions. The invention

BIARYLAMIDE INHIBITORS OF LEUKOTRIENE PRODUCTION

The present invention relates to compounds of formula (I): and pharmaceutically acceptable salts thereof, wherein A, B, C, R1a, R1b, R2, R3, R4a and R4b are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.

PYRIMIDINE DERIVATIVE AS PI3K INHIBITOR AND USE THEREOF

A drug is provided that is useful as a preventive or therapeutic for cancer as a result of having superior PI3K inhibitory effects as well as superior stability in the body and water-solubility. A compound, or pharmaceutically acceptable salt thereof, rep

ARYL-AMINO SUBSTITUTED PYRROLOPYRIMIDINE MULTI-KINASE INHIBITING COMPOUNDS

Compounds represented by Formula (I): or stereoisomers or pharmaceutically acceptable salts thereof, are inhibitors of least two of the Abl, Aurora-A, Blk, c-Raf, cSRC, Src, PRK2, FGFR3, Flt3, Lck, Mekl, PDK-1, GSK3?, EGFR, p70S6K, BMX, SGK, CaMKII, Tie-2