87642-58-8 Usage
Chemical Class
Pyrazole derivatives
Common Uses
Medication for hypertension and cardiovascular diseases
Effects
Potent vasodilatory and antihypertensive
Form
Monomethanesulfonate salt for enhanced solubility and stability in pharmaceutical formulations
Molecule Structure
Contains 1H-pyrazolo[4,3-c]pyridine, 1-butyl, 3-(4-fluorophenyl), 4,5,6,7-tetrahydro groups
Therapeutic Effects
Contributed by the presence of the 4-fluorophenyl group in the molecule
Importance
Potential applications in the medical field as an important chemical entity.
Check Digit Verification of cas no
The CAS Registry Mumber 87642-58-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,7,6,4 and 2 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 87642-58:
(7*8)+(6*7)+(5*6)+(4*4)+(3*2)+(2*5)+(1*8)=168
168 % 10 = 8
So 87642-58-8 is a valid CAS Registry Number.
87642-58-8Relevant academic research and scientific papers
Synthesis, in Vitro 3H>Prazosin Displacement, and in Vivo Activity of 3-Aryl-4,5,6,7-tetrahydropyrazolopyridines, a New Class of Antihypertensive Agents
Winters, Giorgio,Sala, Alberto,Barone, Domenico,Baldoli, Emiliana
, p. 934 - 940 (2007/10/02)
A series of a new 3-aryl-4,5,6,7-tetrahydropyrazolopyridines was synthesized and screened for in vitro 3H>prazosin displacement activity.The results correlated well with their antihypertensive activity in spontaneous hypertensive rats.
