876461-40-4Relevant academic research and scientific papers
Continued exploration of the triazolopyridine scaffold as a platform for p38 MAP kinase inhibition
Jerome, Kevin D.,Rucker, Paul V.,Xing, Li,Shieh, Huey S.,Baldus, John E.,Selness, Shaun R.,Letavic, Michael A.,Braganza, John F.,McClure, Kim F.
scheme or table, p. 469 - 473 (2010/04/05)
The structure based drug design, synthesis and structure-activity relationship of a series of C6 sulfur linked triazolopyridine based p38 inhibitors are described. The metabolic deficiencies of this series were overcome through changes in the C6 linker fr
