87647-62-9Relevant academic research and scientific papers
Phosphinic acid esters and process for preparing the same
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, (2008/06/13)
Disclosed is a novel process for preparing [(3-amino-3-carboxy)-propyl-1]phosphinic acid derivatives, comprising reacting an alkylalkylphosphonyl halide with a vinylmagnesium halide to form a vinylphosphinic acid derivative, and reacting the vinylphosphinic acid derivative with a Shiff's base to form the aimed product. Also disclosed is a novel intermediate compound formed during the course of the above process, which compound has the general formula: STR1 (wherein R1, R2, R3, R4 and R5 are as defined in the specification).
